[Todos] Seminario del dc.uba.ar - Resonancia Magnética Cerebral - DTI

[Demian Wassermann]

Quien: Rachid Deriche, Research Director, INRIA Sophia-Antipolis,
Francia
Que:  Diffusion MRI Processing
Cuando: 12:30, Viernes 10 de Noviembre
Donde: Aula 8, Pabellon 1, Ciudad Universitaria

Abstract:

Diffussion MRI is a Magnetic Resonance Imaging (MRI) modality able
to quantify in vivo and non invasively the diffusion of water molecules
in biological tissues such as the white matter in the brain. This
relatively new imaging modality, pioneered twenty years ago by Denis Le
Bihan (CEA-SHFJ, Paris), acquires at each voxel, image intensities,
referred to as diffusion, related to the relative mobility of endogenous
tissue water molecules and reflecting the structure of the underlying
biological tissues at a microscopic scale, well beyond the usual image
resolution.

In 1994, Peter Basser (NIH, Bethesda), together with J. Mattiello and D.
LeBihan, introduced the formalism of the Diffusion Tensor (DT) and what
is known as DT-MRI. P. Basser proposed to characterize the orientation
dependence of diffusion by an effective self-diffusion tensor given by a
$3 \times 3$ symmetric positive definite tensor ${\bf D}$ and to
estimate it directly from the signal intensities.

In this talk, I will first introduce this recent and exciting imaging
modality and then present the variational approaches we developped for
the estimation, regularization and segmentation of diffusion tensor
images (DTI). These algorithms open the possibility of recovering a
detailed geometric description of the anatomical connectivity between
brain areas and distinguish the anatomical structures of the cerebral
white matter.  Applications to synthetic, phantom and real data sets
from human cerebral white matter structures will illustrate the results
obtained.

In the last part of my talk, I'll conclude by presenting and discussing
some parts of our recent work on tractography and HARDI (High
Angular Resolution Diffusion Imaging)


Short Bio :

Rachid DERICHE graduated from Ecole Nationale Supérieure des
Télécommunications, Paris, in 1979 and received the Ph.D degree in
Mathematics from the University of Paris IX, Dauphine in 1982.

He is currently a Research Director at INRIA Sophia-Antipolis and
performs his research activities in the Odyss\'{e}e laboratory
located in Sophia-Antipolis and Ecole Normale Sup\'erieure, Paris.

His research interests are in Computer Vision and Bilogical Vision and
include Partial Differential Equations, Level-Set techniques,
Variational and Geometrical approaches applied to Image Processing and
Computer and Biological Vision and also the use of functional imaging
with an emphasis on Diffusion MRI for brain image analysis.  More
generally, he is very interested by the application of mathematics to
Computer and Biological Vision and Image Processing. He has authored
and co-authored more than 120 scientific papers and graduated more
than 15 PhD  students.

He has served as the principal investigator in many European projects
since the mid 1980's and acted as area chair, co-organiser or member
of the program comittees of the main conferences in his domain (Iccv,
Eccv, Cvpr, Scale-Space, Icip, Icpr, Caip, Vlsm...). Recently, he has
been local Chair of the 9th ICCV in Nice (Oct 13-17, 2003),
co-organizer of VLSM'2003 (Oct. 11-12, 2003) and area chair for the
7th, 8th and 9th ECCV to be held in May 2006. To find out more about
his research and some selected publications take a look at
http://www-sop.inria.fr/odyssee/team/Rachid.Deriche/index.en.html


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