[Todos] Fw: [Todos QI] HOY SEMINARIO MIERCOLES 20 DE AGOSTO

[Lelia Dicelio]

Miércoles 20 de agosto de 2008 - 13 hs

Aula de Seminarios del INQUIMAE, 3er piso Pab. II 



Dr Randy Duran



Department of Chemistry

University of florida

Gainesville, FL 32611




 

Interfacing Ion Channels to Microelectronics: Comparing Single Channel Activities from Four Systems

  

As part of a project centered on functionally incorporating ion channels in non-native and polymer- stabilized lipid bilayers, we are interested in characterizing the ion translocation behavior of the resulting assemblies.  We have investigated several ion-channels with a view towards using them in tethered bilayers over microelectronic devices for eventual biosensor applications.  The ion channel characteristics and their functional incorporation in bilayers will be presented.  Single channel ion current fluctuations were measured by several methods and these data will be discussed.  Finally methods to tether the ion channel/lipid bilayer assembly to solid state devices and protein-based techniques for stabilization will be presented. 

 





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