[Todos] Seminarios conjuntos IFIBYNE-DFBMC-MARTES 16/9 -12 Hs. - Dres. Ligia Toro y Enrico Stefani

[Paula Felman]

MARTES 16 de septiembre 12 hs. en el aula de seminarios



Seminarios conjuntos de los Dres Ligia Toro y Enrico Stefani

Titulo: "Mitochondrial BKCa Channels"

Resumen: The opening of mitochondrial BKCa channels (mitoBK) is known 
to protect the heart from ischemic insult. In the seminar, we will 
discuss recent advances in mitoBK molecular composition and import to 
mitochondria, and its regulatory role in mitochondrial Ca2+ retention 
capacity. Ligia Toro, PhD. Professor and Dorothy and Leonard Straus 
Scholar Division of Molecular Medicine, Department of Anesthesiology, 
and Department of Molecular & Medical Pharmacology Univeristy of 
California, Los Angeles, USA Title: "Recent advances in 
super-resolution microscopy" Summary: Resolution beyond the 
diffraction limit of ~50 nm can be achieved with Stimulation Emission 
Depletion Microscopy (STED) that is based in bringing to the ground 
state photons in the periphery of the focal spot. One major 
limitation of STED is photobleaching . In the seminar the following 
points will be discussed: 1. A novel system with minimal 
photobleaching with two super-resolution channels based on a fast 
resonant scanning mirror and an ultra-fast photon counting system, 2. 
Mechanisms of photobleaching, 3. Recent discoveries of non-linear 
optical properties of metal nano-particles that can lead to a new 
super-resolution microscopy and 4. Development of a machine learning 
approach for image analysis. Enrico Stefani MD, PhD, Distinguished 
Professor of Anesthesiology and Physiology, John Bartley Dillon 
Endowed Chair in Anesthesiology Dorothy and Leonard Straus Scholar, 
Director, Super Resolution Imaging Center, Associate Director, 
Cardiovascular Research Laboratories David Geffen School of Medicine at UCLA


Host. ODU  
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