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    </p>
    <p>
      <title>MOSAICO Responsive Email Designer</title>
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      <style type="text/css">
    /* CLIENT-SPECIFIC STYLES */
    #outlook a{padding:0;} /* Force Outlook to provide a "view in browser" message */
    .ReadMsgBody{width:100%;} .ExternalClass{width:100%;} /* Force Hotmail to display emails at full width */
    .ExternalClass, .ExternalClass p, .ExternalClass span, .ExternalClass font, .ExternalClass td, .ExternalClass div{line-height: 100%;} /* Force Hotmail to display normal line spacing */
    body, table, td, a{-webkit-text-size-adjust:100%; -ms-text-size-adjust:100%;} /* Prevent WebKit and Windows mobile changing default text sizes */
    table, td{mso-table-lspace:0pt; mso-table-rspace:0pt;} /* Remove spacing between tables in Outlook 2007 and up */
    img{-ms-interpolation-mode:bicubic;} /* Allow smoother rendering of resized image in Internet Explorer */

    /* RESET STYLES */
    body{margin:0; padding:0;}
    img{border:0; height:auto; line-height:100%; outline:none; text-decoration:none;}
    table{border-collapse:collapse !important;}
    body{height:100% !important; margin:0; padding:0; width:100% !important;}

    /* iOS BLUE LINKS */
    .appleBody a{color:#68440a; text-decoration: none;}
    .appleFooter a{color:#999999; text-decoration: none;}

    /* MOBILE STYLES */
    @media screen and (max-width: 525px) {

        /* ALLOWS FOR FLUID TABLES */
        table[class="wrapper"]{
          width:100% !important;
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        /* USE THESE CLASSES TO HIDE CONTENT ON MOBILE */
        td[class="mobile-hide"]{
          display:none;}

        img[class="mobile-hide"]{
          display: none !important;
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        img[class="img-max"]{
          width:100% !important;
          max-width: 100% !important;
          height:auto !important;
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        /* FULL-WIDTH TABLES */
        table[class="responsive-table"]{
          width:100%!important;
        }

        /* UTILITY CLASSES FOR ADJUSTING PADDING ON MOBILE */
        td[class="padding"]{
          padding: 10px 5% 15px 5% !important;
        }

        td[class="padding-copy"]{
          padding: 10px 5% 10px 5% !important;
          text-align: center;
        }

        td[class="padding-meta"]{
          padding: 30px 5% 0px 5% !important;
          text-align: center;
        }

        td[class="no-pad"]{
          padding: 0 0 0px 0 !important;
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        td[class="no-padding"]{
          padding: 0 !important;
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        td[class="section-padding"]{
          padding: 10px 15px 10px 15px !important;
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        td[class="section-padding-bottom-image"]{
          padding: 10px 15px 0 15px !important;
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        /* ADJUST BUTTONS ON MOBILE */
        td[class="mobile-wrapper"]{
            padding: 10px 5% 15px 5% !important;
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        table[class="mobile-button-container"]{
            margin:0 auto;
            width:100% !important;
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        a[class="mobile-button"]{
            width:80% !important;
            padding: 15px !important;
            border: 0 !important;
            font-size: 16px !important;
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</style><!-- PREHEADER -->
      <table id="ko_imageBlock_3" border="0" cellpadding="0"
        cellspacing="0" width="100%">
        <tbody>
          <tr class="row-a">
            <td class="no-pad" style="padding-top: 0px; padding-left:
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              align="center" bgcolor="#17365d">
              <table class="responsive-table" border="0" cellpadding="0"
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                <tbody>
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                      <table border="0" cellpadding="0" cellspacing="0"
                        width="100%">
                        <tbody>
                          <tr>
                            <td>
                              <!-- HERO IMAGE -->
                              <table border="0" cellpadding="0"
                                cellspacing="0" width="100%">
                                <tbody>
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                                        cellspacing="0" width="100%">
                                        <tbody>
                                          <tr>
                                            <td> <img alt=""
                                                class="img-max"
                                                style="display: block;
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                                                src="cid:part1.FBF48C0D.AF7D512B@df.uba.ar"
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        cellspacing="0" width="100%">
        <tbody>
          <tr class="row-a">
            <td class="section-padding" style="padding-top: 30px;
              padding-left: 15px; padding-bottom: 30px; padding-right:
              15px;" align="center" bgcolor="#EDE8DA">
              <table class="responsive-table" border="0" cellpadding="0"
                cellspacing="0" width="500">
                <tbody>
                  <tr>
                    <td>
                      <table border="0" cellpadding="0" cellspacing="0"
                        width="100%">
                        <tbody>
                          <tr>
                            <td>
                              <!-- COPY -->
                              <table border="0" cellpadding="0"
                                cellspacing="0" width="100%">
                                <tbody>
                                  <tr>
                                    <td class="padding-copy"
                                      style="font-size: 28px;
                                      font-family: Helvetica, Arial,
                                      sans-serif; color: #3F3D33;
                                      padding-top: 0px;" align="center">Perseguir
                                      al mensajero</td>
                                  </tr>
                                  <tr>
                                    <td class="padding-copy
                                      textlightStyle" style="padding:
                                      20px 0 0 0; font-size: 16px;
                                      line-height: 25px; font-family:
                                      Helvetica, Arial, sans-serif;
                                      color: #3F3D33;" align="center">
                                      <p style="text-align: justify;"
                                        data-mce-style="text-align:
                                        justify;">Para poder sobrevivir
                                        las células necesitan
                                        comunicarse con el medio que las
                                        rodea. Deben ser capaces de
                                        percibir cambios en su entorno y
                                        reaccionar a los mismos. En una
                                        gran cantidad de circunstancias
                                        esos cambios se manifiestan en
                                        modificaciones en la
                                        concentración de
                                        sustancias.Podemos pensar
                                        entonces que hay un mensaje
                                        cifrado en ese cambio, mensaje
                                        que las células deben poder
                                        descifrar. Para ello poseen
                                        receptores en su membrana
                                        capaces de ligar estas
                                        sustancias. Al ligarlas se
                                        inducen modificaciones hacia el
                                        interior celular constituyendo
                                        el primer paso de una cascada de
                                        señalización que permitirá
                                        transmitir el mensaje y generar
                                        la respuesta necesaria.</p>
                                      <p style="text-align: justify;"
                                        data-mce-style="text-align:
                                        justify;">Los cambios “hacia
                                        adentro” pueden incluir la
                                        producción de nuevas sustancias
                                        o la liberación de otras desde
                                        reservorios internos. Estas
                                        sustancias, a las que se llama
                                        mensajeros, difunden en la
                                        célula y actúan en receptores u
                                        otros blancos intracelulares. Es
                                        por ello que se habla de
                                        “cascada” ya que el cambio
                                        inicial induce una secuencia
                                        encadenada de cambios. Los
                                        mensajeros difunden durante un
                                        tiempo y hasta una cierta
                                        distancia, es decir, tienen un
                                        rango de acción que los
                                        caracteriza. Este rango
                                        determina sobre qué blancos
                                        intracelulares pueden actuar y,
                                        por lo tanto, qué tipos de
                                        respuestas pueden inducir. </p>
                                      <p style="text-align: justify;"
                                        data-mce-style="text-align:
                                        justify;">Conocer estos rangos
                                        permite comprender procesos
                                        fisiológicos específicos. Entre
                                        los múltiples mensajeros
                                        existentes, el ión calcio es
                                        utilizado en una enorme cantidad
                                        de procesos distintos.</p>
                                    </td>
                                  </tr>
                                </tbody>
                              </table>
                            </td>
                          </tr>
                        </tbody>
                      </table>
                    </td>
                  </tr>
                </tbody>
              </table>
            </td>
          </tr>
        </tbody>
      </table>
      <table id="ko_compactarticleBlock_10" border="0" cellpadding="0"
        cellspacing="0" width="100%">
        <tbody>
          <tr class="row-a">
            <td class="section-padding" style="padding: 0px 15px 0px
              15px;" align="center" bgcolor="#17365d">
              <table style="padding: 0 0 20px 0;"
                class="responsive-table" border="0" cellpadding="0"
                cellspacing="0" width="500">
                <tbody>
                  <tr>
                    <td style="padding: 40px 0 0 0;" class="mobile-hide"
                      valign="top"><img alt="" style="display: block;
                        font-family: Arial; color: #3F3D33; font-size:
                        14px; width: 155px;"
                        src="cid:part2.A862ABE1.1A50425B@df.uba.ar"
                        border="0" width="155"></td>
                    <td style="padding: 40px 0 0 0;" class="no-padding">
                      <!-- ARTICLE -->
                      <table border="0" cellpadding="0" cellspacing="0"
                        width="100%">
                        <tbody>
                          <tr>
                            <td class="padding-copy
                              articletextintenseStyle" style="padding:
                              10px 0 15px 25px; font-size: 16px;
                              line-height: 24px; font-family: Helvetica,
                              Arial, sans-serif; color: #ffffff;"
                              align="left">
                              <p style="margin-top:0px"
                                data-mce-style="margin-top: 0px;
                                text-align: center;"> “Aparece en la
                                comunicación entre neuronas; en la
                                excitabilidad neuronal; en la
                                contracción muscular; en la
                                fertilización. Por eso se dice que es un
                                mensajero universal. Pero, por otro
                                lado, es muy específico porque genera
                                respuestas puntuales dependiendo de la
                                célula en la que esté actuando y, aún en
                                una misma célula, da lugar a diferentes
                                respuestas.”<br>
                              </p>
                            </td>
                          </tr>
                          <tr>
                            <td style="padding: 0 0 45px 25px;"
                              class="padding" align="left">
                              <table class="mobile-button-container"
                                border="0" cellpadding="0"
                                cellspacing="0">
                                <tbody>
                                  <tr>
                                    <td align="center">
                                      <!-- BULLETPROOF BUTTON -->
                                      <table
                                        class="mobile-button-container"
                                        border="0" cellpadding="0"
                                        cellspacing="0" width="100%">
                                        <tbody>
                                          <tr>
                                            <td style="padding: 0;"
                                              class="padding-copy"
                                              align="center">
                                              <table
                                                class="responsive-table"
                                                border="0"
                                                cellpadding="0"
                                                cellspacing="0">
                                                <tbody>
                                                  <tr>
                                                    <td align="center">
                                                      <a target="_new"
                                                        class="mobile-button"
                                                        style="display:
                                                        inline-block;
                                                        font-size: 15px;
                                                        font-family:
                                                        Helvetica,
                                                        Arial,
                                                        sans-serif;
                                                        font-weight:
                                                        normal; color:
                                                        #0f243e;
                                                        text-decoration:
                                                        none;
                                                        background-color:
                                                        #f2f2f2;
                                                        padding-top:
                                                        10px;
                                                        padding-bottom:
                                                        10px;
                                                        padding-left:
                                                        20px;
                                                        padding-right:
                                                        20px;
                                                        border-radius:
                                                        3px;
                                                        -webkit-border-radius:
                                                        3px;
                                                        -moz-border-radius:
                                                        3px;
                                                        border-bottom:
                                                        3px solid
                                                        #d3d3d3;"
href="https://www.df.uba.ar/es/investigacion/publicaciones/92-comunicacion/7312-perseguir-al-mensajero">Seguir
                                                        leyendo →</a> </td>
                                                  </tr>
                                                </tbody>
                                              </table>
                                            </td>
                                          </tr>
                                        </tbody>
                                      </table>
                                    </td>
                                  </tr>
                                </tbody>
                              </table>
                            </td>
                          </tr>
                        </tbody>
                      </table>
                    </td>
                  </tr>
                </tbody>
              </table>
            </td>
          </tr>
        </tbody>
      </table>
      <table id="ko_socialBlock_16" border="0" cellpadding="0"
        cellspacing="0" width="100%">
        <tbody>
          <tr class="row-b">
            <td class="section-padding" style="padding: 10px 15px 0px
              15px;" align="center" bgcolor="#EDE8DA">
              <table style="padding: 0 0 0px 0;"
                class="responsive-table" border="0" cellpadding="0"
                cellspacing="0" width="500">
                <tbody>
                  <tr>
                    <td style="padding: 10 10 10px 10px; font-size:
                      25px;" class="padding-copy" align="center"> <a
                        target="_new"
                        href="https://www.facebook.com/DtoFisicaUBA/"><img
                          src="cid:part4.6C9D2947.DDE5FD62@df.uba.ar"
                          alt="Seguici su facebook" style="padding: 0
                          5px 0px 0px;" height="48" width="48"></a> <a
                        target="_new"
                        href="https://twitter.com/Fisica_DFUBA"><img
                          src="cid:part6.B146F22E.03A70E65@df.uba.ar"
                          alt="Seguici su twitter" style="padding: 0 5px
                          0px 5px;" height="48" width="48"></a> </td>
                  </tr>
                </tbody>
              </table>
            </td>
          </tr>
        </tbody>
      </table>
      <!-- FOOTER -->
      <table style="min-width: 500px;" id="ko_footerBlock_2" border="0"
        cellpadding="0" cellspacing="0" width="100%">
        <tbody>
          <tr>
            <td align="center" bgcolor="#eeece1">
              <table align="center" border="0" cellpadding="0"
                cellspacing="0" width="100%">
                <tbody>
                  <tr>
                    <td style="padding: 20px 0px 20px 0px;">
                      <table class="responsive-table" align="center"
                        border="0" cellpadding="0" cellspacing="0"
                        width="500">
                        <tbody>
                          <tr>
                            <td style="font-size: 12px; line-height:
                              18px; font-family: Helvetica, Arial,
                              sans-serif; color: #3F3D33;"
                              align="center" valign="middle"> <span
                                class="appleFooter" style="color:
                                #3F3D33;">Departamento de Física - Fac.
                                de Ciencias Exactas y Naturales<br>
                                 - UBA / Pabellón I, Ciudad
                                Universitaria (1428) - C.A.B.A - <br>
                                Argentina / (54-11) 4576-3390 al 97;
                                Secretaría: 4576-3353; Fax
                                54-11-4576-3357.<br>
                                 <a class="moz-txt-link-freetext" href="https://www.df.uba.ar">https://www.df.uba.ar</a></span><br>
                            </td>
                          </tr>
                          <tr style="text-align: center;">
                            <td><br>
                            </td>
                          </tr>
                        </tbody>
                      </table>
                    </td>
                  </tr>
                </tbody>
              </table>
            </td>
          </tr>
        </tbody>
      </table>
    </p>
  <br /> <table style="border-top: 1px solid #D3D4DE;">
        <tr>
      <td style="width: 55px; padding-top: 18px;"><a href="https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=emailclient" target="_blank"><img src="https://ipmcdn.avast.com/images/icons/icon-envelope-tick-round-orange-animated-no-repeat-v1.gif" width="46" height="29" style="width: 46px; height: 29px;" /></a></td>
                <td style="width: 470px; padding-top: 17px; color: #41424e; font-size: 13px; font-family: Arial, Helvetica, sans-serif; line-height: 18px;">Libre de virus. <a href="https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=emailclient" target="_blank" style="color: #4453ea;">www.avast.com</a>                 </td>
        </tr>
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