<div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div style="font-family:arial,helvetica,sans-serif;font-size:small"><div><span style="font-family:"trebuchet ms",sans-serif;font-size:large">Hola, qué tal!</span><br></div></div><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div><span class="gmail_default"><font face="trebuchet ms, sans-serif" size="4"><br></font></span></div><div><font face="trebuchet ms, sans-serif" size="4"><span class="gmail_default"></span>En el marco de la materia Ingeniería Genética (FBMC,FCEyN, UBA) los invitamos el próximo jueves <b><font color="#0b5394">16 de septiembre a las 18 horas</font></b> a asistir al seminario virtual que dará <b><font color="#351c75">Jonathan Strecker</font></b>, del laboratorio de <b><font color="#274e13">Feng Zhang (Broad Institute, MIT-Harvard)</font></b> acerca de nuevos descubrimientos y potenciales usos de <font>transposasas</font> asociadas a sistemas CRISPR capaces de activar mecanismos de transposición guiados por RNA, de manera similar a la endonucleasa Cas9.<br></font></div><div class="gmail_quote"><div dir="ltr"><div><font face="trebuchet ms, sans-serif" size="4"><br></font></div><div><font face="trebuchet ms, sans-serif" size="4">P<span style="color:rgb(0,0,0)">ara conectarse tienen que ir a <a href="https://zoom.us/my/fbmc.aula05" target="_blank">https://zoom.us/my/fbmc.aula05</a> con la clave </span><font color="#0000ff">exactas20</font><br></font></div><div><font face="trebuchet ms, sans-serif" size="4"><br></font></div><div><font face="trebuchet ms, sans-serif" size="4">El título del seminario será: "<b><font color="#0b5394">Beyond nucleases: the diversity and life cycle of CRISPR-associated transposases</font></b>" y sus publicaciones relacionadas son:</font></div><div style="font-size:small"><font face="trebuchet ms, sans-serif"><br></font></div><div style="font-size:small"><p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;font-size:11pt"><span style="background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><a href="https://pubmed.ncbi.nlm.nih.gov/31171706/" target="_blank"><span style="color:rgb(32,84,147)"><font face="trebuchet ms, sans-serif">RNA-guided
DNA insertion with CRISPR-associated transposases.</font></span></a></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt"><font face="trebuchet ms, sans-serif"><b><span style="color:rgb(33,33,33)">Strecker J</span></b><span style="color:rgb(33,33,33)">, Ladha A, Gardner Z, Schmid-Burgk JL, Makarova KS, Koonin EV,
Zhang F.</span><span style="color:rgb(77,128,85)">Science. 2019 Jul 5;365(6448):48-53.
doi: 10.1126/science.aax9181. Epub 2019 Jun 6.</span></font></p></div><div style="font-size:small"><font face="trebuchet ms, sans-serif"><br></font></div><div><p class="MsoNormal" style="font-size:11pt;margin:0in 0in 0.0001pt;line-height:normal"><a href="https://pubmed.ncbi.nlm.nih.gov/33770501/" target="_blank"><span style="color:rgb(32,84,147);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;text-decoration-line:none"><font face="trebuchet ms, sans-serif">Dual modes of CRISPR-associated
transposon homing.</font></span></a></p>
<p class="MsoNormal" style="font-size:11pt;margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="trebuchet ms, sans-serif"><span style="color:rgb(33,33,33)">Saito M, Ladha A, <b>Strecker
J</b>, Faure G, Neumann E, Altae-Tran H, Macrae RK, Zhang F.</span><span style="color:rgb(77,128,85)">Cell. 2021 Apr 29;184(9):2441-2453.e18. doi:
10.1016/j.cell.2021.03.006. Epub 2021 Mar 25.</span></font></p><p class="MsoNormal" style="font-size:11pt;margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><span style="color:rgb(77,128,85)"><font face="trebuchet ms, sans-serif"><br></font></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="trebuchet ms, sans-serif" size="4">Más información en el flyer adjunto.<br></font></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="trebuchet ms, sans-serif" size="4"><br></font></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="trebuchet ms, sans-serif" size="4">Saludos y nos vemos el jueves online,</font></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="trebuchet ms, sans-serif" size="4"><br></font></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="trebuchet ms, sans-serif" size="4">Marcelo Rubinstein y Elena Avale</font></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="trebuchet ms, sans-serif" size="4">DFBMC, FCEyN. UBA</font></p></div></div>
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