[Todos] Recordatorio seminario LFBM jueves 26 13 hs

[Alejandro Colman-Lerner]

Hola,

Hoy jueves 26 a las 13 hs tenemos un invitado externo para el  
seminario.  Aca va la informacion:

Dr. Tobias Walther
Dept. of Biochemistry and Biophysics, N316
University of California, San Francisco
San francisco, CA 94143
USA


Title: EIsosomes show the door: The discovery of static sites of  
endocytosis in yeast.


Breve descripcion del trabajo:

The plasma membrane is a highly dynamic structure that is constantly  
remodeled by membrane transport events. Exocytosis mediates the  
delivery of lipids and proteins to the surface for cell growth,  
communication, and secretion of cargos. Endocytosis balances the  
delivery of membrane, is essential for the uptake of nutrients and  
pathogens, and mediates the regulation of receptors and transporters.  
To maintain a functional plasma membrane of appropriate composition  
at homeostasis, the cell constantly balances endocytosis and  
exocytosis to compensate for changes in the environment or growth phase.
We recently discovered large protein assemblies, which we call  
³eisosomes², that lay underneath the plasma membrane in the yeast S.  
cerevisiae. Our experiments indicate that eisosomes function as  
static ³endocytic portals² that determine when and where endocytic  
events initiate. The discovery of eisosomes raises many intriguing  
questions, which I intend to address in my group.  How do eisosomes  
affect and regulate endocytosis? How are they targeted to specific  
sites at the plasma membrane and assembled there?

Tobi esta buscando estudiantes de doctorado y/o postdoctorado. Abajo  
les pasteo 2 avisos al respecto. Los interesados, si quieren, pueden  
hablar con el directamente mañana.






Max-Planck-Institute of Biochemistry







PhD Student/Postdoc in Biochemistry/Structural Biology


(reference number: 46.06)


We are looking for a highly motivated and creative PhD student/  
Postdoc for research on assembly of large protein complexes,  
specifically eisosomes. Eisosomes are large protein complexes at the  
plama membrane that mark sites of endocytosis. The major goal of the  
project will be to elucidate the biochemical interactions, assmebly  
pathway and structure of eisosomes . To this end we employ a wide  
spectrum of techniques from cell biology, biochemistry and mass  
spectrometry to EM and crystaloography methods.
Applicants should have a strong research background. The type of  
appointment depends on the level of previous training and experience.

The initial appointment will be for 2 years with the possibility of  
extension.
The Max Planck Society is committed to employing more disabled  
individuals and especially encourages them to apply. It also aims at  
increasing the number of female staff members in fields where they  
are underrepresented, and therefore encourages women to apply.



To apply, please email a curriculum vitae, bibliography, the names  
and addresses of referees to:

Dr. Tobias Walther
Organelle Architecture and Dynamics Group
Max Planck Institute of Biochemistry
Am Klopferspitz 18
82152 Martinsried/Munich
twalther en biochem.mpg.de








Max-Planck-Institute of Biochemistry







PhD Student/Postdoctoral Fellows in Systems Biology



(reference number: 47.06)




We are looking for a highly motivated and creative PhD student/ 
Postdoc for research on plasma membrane dynamcis and endocytosis. The  
major goal of the project is to elucidate the molecular function of  
eisosomes. To this end we employ a wide spectrum of techniques from  
high throughput genetics, bioinformatics to cell biology and  
biochemistry. This project is based on collaboration with Nevan  
Krogan’s laboratory (QB3/UCSF) and Pablo Aguilar  
(Inst.Pasteur,Montevideo) might necessitate short-term work in the  
partner laboratories.
Applicants should have a strong research background. The type of  
appointment depends on the level of previous training and experience.

The initial appointment will be for 2 years with the possibility of  
extension.

The Max Planck Society is committed to employing more disabled  
individuals and especially encourages them to apply. It also aims at  
increasing the number of female staff members in fields where they  
are underrepresented, and therefore encourages women to apply.




To apply, please email a curriculum vitae, bibliography, the names  
and addresses of referees to:

Dr. Tobias Walther
Organelle Architecture and Dynamics Group
Max Planck Institute of Biochemistry
Am Klopferspitz 18
82152 Martinsried/Munich
twalther en biochem.mpg.de



Saludos,

Los ministros: Alejandro Colman-Lerner y Fernando Marengo
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