[Todos] Seminario LFBM hoy a las 13 hs

[Alejandro Colman-Lerner]

Hola,

Hoy jueves 26 a las 13 hs tenemos un invitado externo para el  
seminario.  Aca va la informacion:

Dr. Tobias Walther
Dept. of Biochemistry and Biophysics, N316
University of California, San Francisco
San francisco, CA 94143
USA


Title: EIsosomes show the door: The discovery of static sites of  
endocytosis in yeast.


Breve descripcion del trabajo:

The plasma membrane is a highly dynamic structure that is constantly  
remodeled by membrane transport events. Exocytosis mediates the  
delivery of lipids and proteins to the surface for cell growth,  
communication, and secretion of cargos. Endocytosis balances the  
delivery of membrane, is essential for the uptake of nutrients and  
pathogens, and mediates the regulation of receptors and transporters.  
To maintain a functional plasma membrane of appropriate composition  
at homeostasis, the cell constantly balances endocytosis and  
exocytosis to compensate for changes in the environment or growth phase.
We recently discovered large protein assemblies, which we call  
³eisosomes², that lay underneath the plasma membrane in the yeast S.  
cerevisiae. Our experiments indicate that eisosomes function as  
static ³endocytic portals² that determine when and where endocytic  
events initiate. The discovery of eisosomes raises many intriguing  
questions, which I intend to address in my group.  How do eisosomes  
affect and regulate endocytosis? How are they targeted to specific  
sites at the plasma membrane and assembled there?

Tobi esta buscando estudiantes de doctorado y/o postdoctorado. Abajo  
les pasteo 2 avisos al respecto. Los interesados, si quieren, pueden  
hablar con el directamente mañana.

Los ministros
Alejandro Colman Lerner
Fernando Marengo
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